surgeon can make a larger cut. Sometimes doctors can use special techniques that require smaller cuts for these biopsies. Once the lymph node is removed, a doctor will check to see if it has one of the types of tissue that is associated with Castleman’s disease, hyaline-vascular or plasma cell (Castleman's Disease).
Affected Population Castleman’s disease is a rare disorder that can affect the male and female population equally. A person is also able to contract the disease at any age, but it is more common in younger males and females. Children however, are rarely diagnosed with Castleman’s disease. Healthy people rarely get the disease, but those with preexisting immune issues are more at risk of being affected. Persons with any type of …show more content…
The first and most used treatment is surgery. Unicentric Castleman’s disease can be most easily cured by surgically removing the diseased lymph node. If the lymph node is in the patient’s chest or abdomen, which is often the case, major surgery may be required. With multicentric Castleman’s disease surgery is not usually the first option. The larger the masses are, the greater the chance the surgery will be a success. Sometimes with multicentric Castleman’s disease, there are too many small masses that a traditional surgery is not possible, so other forms of treatment are used (New treatment for Castleman's …show more content…
Some of the most commonly used prescriptions are Corticosteroids, powerful drugs that reduce inflammation, and an immunotherapy drug called rituximab (Rituxan). Rituximab latches onto a specific protein on the surface of some lymph cells, causing them to die. These drugs can be used for any type of Castleman’s disease, but are most commonly used in unicentric cases (About Castleman Disease). Multicentric Castleman’s disease sometimes requires a more aggressive medicine that can shrink spots that cover many areas of the body. The doctors first introduce a drug that can turn down the immune system, called immunosuppressants. Some doctors use a drug called cyclosporine to slow down the growth and activity of immune cells called T cells. With the connection of the patients possibly having HIV, the doctor may also give the patient an antiviral drug. With the extra diagnosis of HIV or HHV-8 infection, these medicines can fight these viruses. Antivirals that are used include foscarnet, ganciclovir, and valganciclovir (Castleman
Affected Population Castleman’s disease is a rare disorder that can affect the male and female population equally. A person is also able to contract the disease at any age, but it is more common in younger males and females. Children however, are rarely diagnosed with Castleman’s disease. Healthy people rarely get the disease, but those with preexisting immune issues are more at risk of being affected. Persons with any type of …show more content…
The first and most used treatment is surgery. Unicentric Castleman’s disease can be most easily cured by surgically removing the diseased lymph node. If the lymph node is in the patient’s chest or abdomen, which is often the case, major surgery may be required. With multicentric Castleman’s disease surgery is not usually the first option. The larger the masses are, the greater the chance the surgery will be a success. Sometimes with multicentric Castleman’s disease, there are too many small masses that a traditional surgery is not possible, so other forms of treatment are used (New treatment for Castleman's …show more content…
Some of the most commonly used prescriptions are Corticosteroids, powerful drugs that reduce inflammation, and an immunotherapy drug called rituximab (Rituxan). Rituximab latches onto a specific protein on the surface of some lymph cells, causing them to die. These drugs can be used for any type of Castleman’s disease, but are most commonly used in unicentric cases (About Castleman Disease). Multicentric Castleman’s disease sometimes requires a more aggressive medicine that can shrink spots that cover many areas of the body. The doctors first introduce a drug that can turn down the immune system, called immunosuppressants. Some doctors use a drug called cyclosporine to slow down the growth and activity of immune cells called T cells. With the connection of the patients possibly having HIV, the doctor may also give the patient an antiviral drug. With the extra diagnosis of HIV or HHV-8 infection, these medicines can fight these viruses. Antivirals that are used include foscarnet, ganciclovir, and valganciclovir (Castleman