Emilyn Nguyen
Bad Blood – A Cautionary Tale – High School Version
Test Grade (33 Points): Answer the following questions after completely viewing the movie. Some answers may require additional research. Include a work cited using MLA format and parenthetical documentation throughout your writing.
1. What is hemophilia? What is its cause and symptoms? Which factors are low or missing in the person? Why are a person’s joints are often affected?
Hemophilia is a genetic disorder in which a person has an absence of blood clotting proteins/factors, causing their blood to clot abnormally (Bad Blood). Those with this disorder have a tendency to bleed for longer periods of time compared to people with normal clotting proteins/factors (Mayo Clinic). …show more content…
The discovered Cryo researchers noticed what was settling at the bottom of a bag of plasma for transfusion. They found that this substance which came to be known as Cryo, contained many times more blood clotting factors than in the plasma, and could be used in fewer substitutions than a several bags of plasma (Bad Blood).
4. In1966 Cryo was turned into Factor. What is Factor? How is it produced? Why did Factor have a much higher risk of disease transmission than Cryo?
Factor is a treatment to help stop or prevent people with hemophilia. Today, factor is produced by genetically engineering the blood clotting factors VIII, and IX. These genes have the instructions to make human factor to help the blood clot. Another way they create Factor is from human plasma. Donations are brought together in one barrel and then separated into different products. This was the reason that Factor had a higher risk of disease transmission than Cryo did, because if one blood donor had a disease, the whole barrel that it was put in would be infected as well. Cryo was derived from plasma but from each donor individually, while plasma was pooled together, which meant that if one person had HIV than everyone in that pool would be infected (Bad …show more content…
HCV is a disease the effects the liver slowly over a period of time. The virus persists in the site of the liver over a long period of time, so that the patients may not know that he/she has HCV. Over this period of time, the patient will develop fibrosis and cirrhosis which is permanent scarring and scarring to the liver tissue. This damage is ‘silent’, and many times patients do not know that this damage has occurred. After cirrhosis occurs, the liver is unable to heal itself leading patients to have “Stage 4 Hepatitis C” (CDC: Hepatitis C). By this point, depending on the severity of the patient’s HCV, patients usually take a combination of medications such as Sovaldi, Olysio, Incivek, Victreli, and Viekira Pak to manage their HCV, but never completely treat it (Mayo Clinic). In addition however, many of these patients were also infected with Human Immunodeficiency Virus (HIV). During the 1900s, HIV was one of the most significant viral infections in patients, and HCV was underestimated in significance. Once HIV was controlled through highly active antiretroviral treatment (HAART), some of these patients were found to be co infected with HCV, increasing the awareness of HCV. Today, 3.2 million people in the United States have HCV.
Bad Blood – A Cautionary Tale – High School Version
Test Grade (33 Points): Answer the following questions after completely viewing the movie. Some answers may require additional research. Include a work cited using MLA format and parenthetical documentation throughout your writing.
1. What is hemophilia? What is its cause and symptoms? Which factors are low or missing in the person? Why are a person’s joints are often affected?
Hemophilia is a genetic disorder in which a person has an absence of blood clotting proteins/factors, causing their blood to clot abnormally (Bad Blood). Those with this disorder have a tendency to bleed for longer periods of time compared to people with normal clotting proteins/factors (Mayo Clinic). …show more content…
The discovered Cryo researchers noticed what was settling at the bottom of a bag of plasma for transfusion. They found that this substance which came to be known as Cryo, contained many times more blood clotting factors than in the plasma, and could be used in fewer substitutions than a several bags of plasma (Bad Blood).
4. In1966 Cryo was turned into Factor. What is Factor? How is it produced? Why did Factor have a much higher risk of disease transmission than Cryo?
Factor is a treatment to help stop or prevent people with hemophilia. Today, factor is produced by genetically engineering the blood clotting factors VIII, and IX. These genes have the instructions to make human factor to help the blood clot. Another way they create Factor is from human plasma. Donations are brought together in one barrel and then separated into different products. This was the reason that Factor had a higher risk of disease transmission than Cryo did, because if one blood donor had a disease, the whole barrel that it was put in would be infected as well. Cryo was derived from plasma but from each donor individually, while plasma was pooled together, which meant that if one person had HIV than everyone in that pool would be infected (Bad …show more content…
HCV is a disease the effects the liver slowly over a period of time. The virus persists in the site of the liver over a long period of time, so that the patients may not know that he/she has HCV. Over this period of time, the patient will develop fibrosis and cirrhosis which is permanent scarring and scarring to the liver tissue. This damage is ‘silent’, and many times patients do not know that this damage has occurred. After cirrhosis occurs, the liver is unable to heal itself leading patients to have “Stage 4 Hepatitis C” (CDC: Hepatitis C). By this point, depending on the severity of the patient’s HCV, patients usually take a combination of medications such as Sovaldi, Olysio, Incivek, Victreli, and Viekira Pak to manage their HCV, but never completely treat it (Mayo Clinic). In addition however, many of these patients were also infected with Human Immunodeficiency Virus (HIV). During the 1900s, HIV was one of the most significant viral infections in patients, and HCV was underestimated in significance. Once HIV was controlled through highly active antiretroviral treatment (HAART), some of these patients were found to be co infected with HCV, increasing the awareness of HCV. Today, 3.2 million people in the United States have HCV.