1.1 Caenorhabditis elegans (C. elegans)
Caenorhabditis elegans is a free-living non-parasitic, non-infectious, non-pathogenic, transparent Nematode (roundworm). It has a full grown length of about 1mm, a life span of around 3 weeks and is found in temperate soil environments where it survives by feeding on microbes such as bacteria. [1]
Consisting of about 1000 somatic cells as an adult, C. elegans is amenable to genetic crosses and produces a large number of progeny, at times even exceeding 1000 per adult, with a life cycle of up to 3 days, under optimal conditions
There are two known sexes of C. elegans, a self-fertilizing hermaphrodite (XX) and a male (XO). Self-fertilization of the hermaphrodite leads to genetically identical progeny …show more content…
elegans an ideal model organism for studying the genetics of behaviour, development and neuroscience. The reproductive cycle (four larval stages) lasts for just up to three and half days while each organism is capable of yielding about 300 progenies. The fact that Hermaphrodites can reproduce either by cross- or self-fertilisation allows for the viability of mutant strains even without mating behaviour and even paralysed worms with an absent nervous system function can be grown in the laboratory, allowing the analysis of strains with mutations such as synaptic vesicle proteins and voltage-gated channels. …show more content…
The software used the programming language BASIC09. The system was later improved by Dusenbery and his colleagues in order that it could further track 100s of animals utilizing the NIH Image software. [14]. Meanwhile, the Cori Bargmann lab developed a capable of tracking 50 animals utilizing the “DIAS” software program to study the neuropeptide Y receptor NPR-1 and its role in aggregation behaviour. The recorded videos were analysed and the speed of the organisms was calculated as an average over a given period of time or between successive frames.
Caenorhabditis elegans is a free-living non-parasitic, non-infectious, non-pathogenic, transparent Nematode (roundworm). It has a full grown length of about 1mm, a life span of around 3 weeks and is found in temperate soil environments where it survives by feeding on microbes such as bacteria. [1]
Consisting of about 1000 somatic cells as an adult, C. elegans is amenable to genetic crosses and produces a large number of progeny, at times even exceeding 1000 per adult, with a life cycle of up to 3 days, under optimal conditions
There are two known sexes of C. elegans, a self-fertilizing hermaphrodite (XX) and a male (XO). Self-fertilization of the hermaphrodite leads to genetically identical progeny …show more content…
elegans an ideal model organism for studying the genetics of behaviour, development and neuroscience. The reproductive cycle (four larval stages) lasts for just up to three and half days while each organism is capable of yielding about 300 progenies. The fact that Hermaphrodites can reproduce either by cross- or self-fertilisation allows for the viability of mutant strains even without mating behaviour and even paralysed worms with an absent nervous system function can be grown in the laboratory, allowing the analysis of strains with mutations such as synaptic vesicle proteins and voltage-gated channels. …show more content…
The software used the programming language BASIC09. The system was later improved by Dusenbery and his colleagues in order that it could further track 100s of animals utilizing the NIH Image software. [14]. Meanwhile, the Cori Bargmann lab developed a capable of tracking 50 animals utilizing the “DIAS” software program to study the neuropeptide Y receptor NPR-1 and its role in aggregation behaviour. The recorded videos were analysed and the speed of the organisms was calculated as an average over a given period of time or between successive frames.