Burkitt’s Lymphoma is a form of non-Hodgkin’s lymphoma in which cancer starts in the immune system called B-cells. It affects the lymphatic system, which helps your body fight infections. There are two common types: Sporadic and Endemic. The types differ by the parts of the body affected and the geographic location. Cause:
The disorder is caused by chromosomal translocations. It is also associated with impaired immunity. The endemic (African) type is linked to the Epstein-Barr virus, HIV, and malaria. Malaria weakens the immune system’s response to Epstein-Barr, which allows it to change infected B-cells into cancerous cells.
Chromosome affected:
The c-myc gene on chromosome 8 is affected.
Symptoms:
Symptoms include fever, night sweats, swollen lymph nodes, intestinal …show more content…
It is not inherited. It is a random gene mutation caused by changes in chromosome 8 and exchanges of genetic material (translocation).
Population affected:
It is most often seen in males. It is most common in Africa. It occurs between the ages of 7 and 11, but can occur at any age. People who have HIV and weak immune systems are also candidates.
Can individual have children and will children be affected?
Yes, the individual can have children. Their children will not be affected, because non-Hodgkin lymphoma is not hereditary.
Medical Assistance:
Chemotherapy, surgery, radiation, and stem cell transplant is needed. A child’s prognosis will depend on the extent of the disease and tumor, their age and health, and the treatments available.
Life Expectancy:
In children, intensive chemotherapy usually cures the cancer, leading to long-term survival rates of 60%-90%. In adults, long-term survival rates are about 70% to 80%.
Are there prenatal tests?
Yes. Some include a bone marrow biopsy, chest x-ray, and lymph node biopsy. You can also get a CT scan of the chest, abdomen, and pelvis.
Could the disorder be
The disorder is caused by chromosomal translocations. It is also associated with impaired immunity. The endemic (African) type is linked to the Epstein-Barr virus, HIV, and malaria. Malaria weakens the immune system’s response to Epstein-Barr, which allows it to change infected B-cells into cancerous cells.
Chromosome affected:
The c-myc gene on chromosome 8 is affected.
Symptoms:
Symptoms include fever, night sweats, swollen lymph nodes, intestinal …show more content…
It is not inherited. It is a random gene mutation caused by changes in chromosome 8 and exchanges of genetic material (translocation).
Population affected:
It is most often seen in males. It is most common in Africa. It occurs between the ages of 7 and 11, but can occur at any age. People who have HIV and weak immune systems are also candidates.
Can individual have children and will children be affected?
Yes, the individual can have children. Their children will not be affected, because non-Hodgkin lymphoma is not hereditary.
Medical Assistance:
Chemotherapy, surgery, radiation, and stem cell transplant is needed. A child’s prognosis will depend on the extent of the disease and tumor, their age and health, and the treatments available.
Life Expectancy:
In children, intensive chemotherapy usually cures the cancer, leading to long-term survival rates of 60%-90%. In adults, long-term survival rates are about 70% to 80%.
Are there prenatal tests?
Yes. Some include a bone marrow biopsy, chest x-ray, and lymph node biopsy. You can also get a CT scan of the chest, abdomen, and pelvis.
Could the disorder be