Purpose: For a person with a positive mutation in BRCA1 or BRCA2, the chance of getting breast cancer increases by 50-60 percent.1 This causes concern for some women and makes them take a BRCA1/2 mutation test to make sure they are not carrying this mutation. In September 2015, a research from UCLA was published that indicated some debate over whether or not testing BRCA genes is worth the cost.4 This paper will be reviewing the evidence from Dr. Ganz et al. about the breast cancer testing. In addition, this paper contains some other research related to the topic, including my own research and perception.
Introduction
Cancer happens when the cells in the body grow …show more content…
This is a solution to prevent the cancer from developing, therefore eliminating the need for chemotherapy 4. Moreover, salpingo-oophorectomy,which is a surgery in order to remove the fallopian tube and ovary, can reduce the risk of cancer in both breast and ovarian cancers. 12
Knowing whether or not an individual is positive for BRCA1 or BRCA2 mutations can also influence their decisions about reproduction. Some of the women choose to do oocyte recovery and genetic testing before conducting embryo implantation4 , which I believe some of these behaviors, are considered unnecessary fears. There are chances that the mutation will not go to next generation or breast cancer does not …show more content…
In my study I found out there non BRCA genes related with breast cancer which emphasizes that other genes are as important as BRCA and harmful mutations in those genes can result in having the same problem.
In addition, breast cancer can be caused by the other risk factors such as the environment which is if the person is smoking, she/he is obese, or UV radiation from the sun, and drinking alcohol.
Another fact that I looked at was the chance of someone with positive mutation to have breast cancer. The studies suggest that for 65 percent of the women with destructive mutation in BRCA1 and 45 percent with destructive mutation BRCA2 mutation, breast cancer will get breast cancer by the time they are 70.1 In other word, there is 35-50 percent hope people with positive mutation never have breast cancer and importantly they showed breast cancer at the old age.
Moreover, considering that harmful BRCA1 and BRCA2 mutations are rare in most racial/ ethnic populations. Most experts believe that genomic testing should not be implemented on everybody and it is better to carry out only on those people who have a family history of breast or ovarian