Particularly, silver nanoparticles (AgNPs) have shown excellent antimicrobial activity and have been used as antimicrobial agents in public places such as railroad stations and elevators in China [10]. Advances in silver nanoparticle development has revived the use of AgNPs as bactericidal agents. Medical applications of AgNPs include bactericidal coatings in air filters and antimicrobial agents in sanitizer sprays, pillows, respirators, socks, shampoos, washing machines, bone cements, catheters, neurosurgical shunts, etc. [7, …show more content…
They investigated the synthesis of silver nanoparticles by the spore crystal mixture of Bacillus thuringiensis (Bt). Bt had been used because of its ease of availability and lack of seasonal dependence. The Bt strain IS1 was isolated from the soils of Bikaner, Rajasthan and was added to a mixture of silver nitrate to form silver nanoparticles [5]. The AgNPs synthesized were found highly toxic against many different multi-drug resistant human pathogens: Escherichia coli, Pseudomonas aeruginosa, and Streptococcus aureus. These silver nanoparticles even exhibited greater antibacterial activity than standard antibiotics [5]. This investigation showed how bacterial endospores have the potential of being excellent bactericidal agents against multi-drug resistant pathogens which is important in the context of healthcare associated