Long-term opioid use can put the patient at risk too many medication-related problems. The use of anticonvulsant drugs is commonly used for seizures, but helps reduce some chronic and cancer pain. Anticonvulsants are also adjuvant analgesics because they don’t allow certain type of nerve transmissions therefore changing the way the body senses pain. Anticonvulsant may be taken alone for pain management in combination with opioids. Common drugs gabapentin and pregabalin (Lyrica) are considered first-line medications in various types of neuropathic pain and to treat migraine headaches. Gabapentin is initially started at a lower dose (300 to 600 mg per day) to limit side effects such as drowsiness and dizziness and titrated as tolerated. Other
