The authors, S.H. Barage and K.D. Sonawane, have conducted tests and have gone through countless hours of research at Shivaji University, to test their hypothesis that it is in fact the Amyloid Beta peptides that cause the accumulation of Alzheimer’s disease. As the Amyloid Beta hypothesis states, “accumulation of amyloid beta plaques acts as a pathological trigger for a cascade that includes neuritic injury”. Because of these cascaded actions, tau proteins build up in abnormal amounts on the brain, causing cellular death that later leads to Alzheimer’s disease or severe neurological trauma. The tau proteins and the Amyloid Beta peptide chain are the two main factors that cause the over production and malfunction in the brain’s decline to Alzheimer’s.
