6. Coumadin
Classification: Vitamin K Antagonists
Clinical uses and indications:
The drug Coumadin is used to prevent and treat venous thrombosis, pulmonary embolism, and according towww.rxlist.com, “thromboembolic risks associated with atrial fibrillation and cardiace valve replacement.“ Coumadin also helps reduce the risk of death, myocaridal infartion, and strokes. (www.rxlist.com/coumadin)
Normal dosages:
Coumadin requires “individualized patient dosage“ (www.rxlist.com) as each patient’s international normalized response (INR) will be different. However, according Physicans Desk Reference (www.pdr.net), adults who do not have any known risks for enhanced INR to warfarin may take two to five milligrams (2-5 mg) by mouth, once daily. Depending …show more content…
The website www.drugbank.com further explains Singulair’s mode of action as, “Montelukast blocks the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it.” (www.drugbank.com) To summarize, Montelukast blocks leukotriene, which causes bronchoconstriction, thus decreasing the amount of inflammation.
Adverse Effects o Severe
• Churg-Strauss syndrome, vasculitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, pancreatitis, erythema nodosum, anaphylactoid reactions, angioedema, suicidal ideation, seizures, o Moderate
• Pyuria, atopic dermatitis, myopia, wheezing, gastritis, conjunctivitis, elevated hepatic enzymes, eosinophilia, hepatitis, edema, thrombocytopenia, palpitations, bleeding, memory impairment, confusion, depression, hostility, hallucinations, urinary incontinence o Mild
• Dizziness, fatigue, asthenia, nasal congestion, nausea, dyspepsia, rash, vomiting, sinusitis, fever, laryngitis, pharyngitis, abdominal pain, headache, cough, urticaria, infection, diarrhea, rhinitis, rhinorrhea, epistaxis, influenza, myalgi, weight loss, pruritus, arthralgia, hypoesthesia,muscle cramps, drowsiness, paresthesias, ecchymosis, somnambulism, anxiety, restlessness,irritability, tremor, agitation, nightmares,
Classification: Vitamin K Antagonists
Clinical uses and indications:
The drug Coumadin is used to prevent and treat venous thrombosis, pulmonary embolism, and according towww.rxlist.com, “thromboembolic risks associated with atrial fibrillation and cardiace valve replacement.“ Coumadin also helps reduce the risk of death, myocaridal infartion, and strokes. (www.rxlist.com/coumadin)
Normal dosages:
Coumadin requires “individualized patient dosage“ (www.rxlist.com) as each patient’s international normalized response (INR) will be different. However, according Physicans Desk Reference (www.pdr.net), adults who do not have any known risks for enhanced INR to warfarin may take two to five milligrams (2-5 mg) by mouth, once daily. Depending …show more content…
The website www.drugbank.com further explains Singulair’s mode of action as, “Montelukast blocks the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it.” (www.drugbank.com) To summarize, Montelukast blocks leukotriene, which causes bronchoconstriction, thus decreasing the amount of inflammation.
Adverse Effects o Severe
• Churg-Strauss syndrome, vasculitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, pancreatitis, erythema nodosum, anaphylactoid reactions, angioedema, suicidal ideation, seizures, o Moderate
• Pyuria, atopic dermatitis, myopia, wheezing, gastritis, conjunctivitis, elevated hepatic enzymes, eosinophilia, hepatitis, edema, thrombocytopenia, palpitations, bleeding, memory impairment, confusion, depression, hostility, hallucinations, urinary incontinence o Mild
• Dizziness, fatigue, asthenia, nasal congestion, nausea, dyspepsia, rash, vomiting, sinusitis, fever, laryngitis, pharyngitis, abdominal pain, headache, cough, urticaria, infection, diarrhea, rhinitis, rhinorrhea, epistaxis, influenza, myalgi, weight loss, pruritus, arthralgia, hypoesthesia,muscle cramps, drowsiness, paresthesias, ecchymosis, somnambulism, anxiety, restlessness,irritability, tremor, agitation, nightmares,