Actinic Keratosis Research Papers

Actinic Keratosis (AK) is a skin disease in which lesions form on the skin due to being over-exposed to ultraviolet light rays. This disease may develop into Squamous Cell Carcinoma (SCC). AK is usually pretty common lesions on the skin that are usually red, brown, or nude colored, rough patches on the skin that has been over-exposed to UV light rays. The more of AK that a person has, the more of a risk the person has of developing melanoma skin cancer. As AK grows and develops, it can become thicker and become larger, and can develop into SCC. There has been use of lesion and field-directed therapy to help treat AK in smaller areas. This therapy can help lower the actinic damage and will be able to tell whether or not the person is susceptible for SCC. There were a handful of people that were willing to undergo a treatment using Ingenol …show more content…
The small use of Ingenol mebutate gel on a person shortly after a cryosurgery showed that they were able to withstand the gel and showed that areas affected by AK was clearing up after using the gel prior to the conclusion of the surgery. The clinical amounts of the gel used by the people undergoing the treatment were 0.015% and 0.05%. The gel helped to clear those areas much better than having just the surgery on its own. It was between the months of August 2012 and October 2013 and there were 7 people in total that did the treatment. The people that have been tested with Ingenol mebutate were of different ages and sex, and had different histories with AK over the years. There were 10 persistent lesions that were found on 6 men and 1 woman. All 7 of those people had had a history with AK and had prior cryosurgery. Two weeks after having cryosurgery on the face or the scalp area, the people undergoing treatment started using Ingenol mebutate once a day on the infected areas. Some of the people underwent more trials of using the Ingenol