PY= (Final wt. /Initial wt.) *100= (1.693 g/3.113 g) *100
Formula 1
Ethyl vinyl ether was used to protect –OH on glycidol based on a literature reported protocal.59 In a typical procedure, 0.675 mol glycidol and 200 mL ethyl vinyl ether were loaded in a round-bottom flask, to which 1.25 g TsOH was then added. The reaction was allowed to proceed at room temperature (RT) for 3h. The resulting mixture was then purified by washing with 100 ml saturated aqueous solution of NaHCO3 for 3 times. The organic layer obtained was dried by MgSO4. After filtration of MgSO4, the excess ethyl vinyl ether was removed by rotary evaporation.…
2 Experimental Before coming into the lab, a stoichiometry table was created with information for each reagent and product. Table 1: Stoichiometry Table Reagents Mass/Volume Molecular Weight (g/mol) Moles Mole Ratio 9-fluorenone 0.6 g 180.20 0.0033 2.5 NaBH4 0.05 g 37.83 0.0013…
DISCUSSION 2-Bromoheptane + Potassium TertButoxide The 2-Bromoheptane + Potassium TertButoxide reaction yielded 3 different products: 1-heptene, Cis-2-heptene and Trans-2-heptene. However, the major product constituent was 1-heptene. Because Potassium TertButoxide is a bulky base, steric hindrance prevents it from attacking a hydrogen on a highly substituted carbon.…
The instructor checked the apparatus and then put in 8 mL of anhydrous ether. The 4.5 mL of bromobenzene was added to the flask to make the Grignard reagent. The instructor added 12 mL of ether after the reaction changed colors clear to dark brown. The reaction was left to react for 30 minutes. During this time, 2.3 mL of methyl benzoate was obtained in a graduated cylinder and…
The purpose of this lab was to iodonize salicylamide and characterize the product in order to determine its structure. The crude product of this reaction was recrystallized using ethanol. The white crystalline product was isolated using vacuum filtration and characterized. The percent yield of this reaction was determined to be 39%. The observed experimental melting point of the product was determined to be 235-137 oC. When compared to the literature melting point 228 oC of the predicted product, 5-iodosalicylamide, it can be concluded that the product is very pure.…
There are three possible outcomes when 2-ethyl-1,3-hexanediol undergoes the oxidation reaction (Scheme 2, Scheme 3, and Scheme 4). (2) Scheme 2. The first possible product when 2-ethyl-1,3-hexanediol undergoes oxidation reaction. (3) Scheme 3. The second possible product when 2-ethyl-1,3-hexanediol undergoes oxidation reaction.…
The objective of this experiment was to oxidize 9-fluorenol with bleach to form 9-fluorenone. This was done with three different reactions, each under different conditions. The reactions were evaluated using the TLC plate to see how far each reaction progressed. During the experiment reaction test tube 2 had the darkest yellow color out of the three reactions.…
There were sp3 C-H peaks in the 2800-3100cm-1, sp2 C-H peaks in the 3100cm-1 range and C= C peaks in the 1620-1680cm-1. The conditions of this lab favored thermodynamic, since the reaction was under thermodynamic control that means the product with lost energy forms in the largest yield. 1-methylcyclohexene is the thermodynamic product because it is the most stable. The percent yield of product was 14.8 percent and the theoretical yield was 0.583g.…
Lastly, for the synthesis reaction, this procedure begins by adding 4.571 g of K2CO3 and 3.68 g of CaCl2 into two different beakers containing 50mL of water each. Following this, the two solutions must be combined and mix thoroughly. Using a filtration device, the KCl(aq) must be separated from the CaCO3(s). After this is done, place the solution atop a hot plate and put at setting 5. Boil the solution until all of the liquid has evaporated.…
Initially, the Pictet-Spengler reactions were scrutinized with tryptamine and glutaraldehyde by a variety of organocatalysts in different solvents (such as CH2Cl2 and H2O). Unsuccessfully, the reactions were in vain with the recovery of tryptamine and the decomposition of glutaraldehyde. In addition, the attempt of the reaction of tryptaminecarbamate and 5-hydroxypentanal with DPP and TFA in CH2Cl2 was fruitless and gave complicate…
This very low amount of benzoic acid recovered could have been caused by a number of possibilities. Some of the components may have been lost throughout the extraction process, some of the component may have stuck to the inside of the reaction tube or the filter paper used in vacuum extraction, or may have been human error in recording the masses. In all of these occurrences may have contributed to the recovery loss of benzoic acid. Conclusions Overall, all three components benzoic acid, 4’-acetylbenzonitrile, and 4’-aminoacetophenone were recovered in very pure forms as melting point determinations and 1H NMR analyses were very clear and did not experience many shifts or deviations from what was to be expected.…
A sample of this reaction mixture (100 μL) was added to dichloromethane (0.5 mL). Potassium carbonate (5 mL, 5 mmol) was added to the rest of the reaction mixture which was then placed in the sonication bath. A sample of the dichloromethane layer (100 μL) was extracted out every 8 minutes and added to dichloromethane (0.5 mL) until the 32nd minute. All the samples, along with benzaldehyde and ethyl cinnamate solutions were analysed by TLC with the eluent prepared from hexane (8 mL) and dichloromethane (2 mL), and then stained with…
Allergies, at some point, affects everyone in some way or another. Whether it’s allergic rhinitis, skin allergies, food allergies, latex, pets, insects, or drug allergies, it’s a major concern. However, the bigger problem lies in the solution. Not because it’s hard to solve but because the solution comes with a price. The price possibly being brain damage.…
One important aspect of organic chemistry is the synthesis of new compounds. It is also important for chemists to understand how to perform certain techniques, such as extraction and distillation, to produce the new products, which are usually drugs and cures for illnesses. In this experiment, n-butyl bromide was produced. n-Butyl bromide is an alkyl halide, which are usually synthesized by an alcohol and an acid. In the case of n-butyl bromide, n-butyl alcohol was used along with sodium bromide and sulfuric acid.…
Observed/theoretical X 100 1.476 g/3.08 g X 100=47.9% Discussion of Results: There was too much error introduced into the experiment to be able to indicate exactly which product was obtained through the experiment. I believe the results were supposed to include the product being erythro-2,3-dibromo-3-phenypropanoic acid and the mechanism that took place in the experiment was in fact the bromonium ion mechanism. My group’s percent error was 47.9% which is extremely low. This low percent error was gained from the lack of mass of the product obtained after vacuum filtration.…