• Home Page
  • 2 Methylcyclohexanon To Sodium Borohydride Di

2 Methylcyclohexanon To Sodium Borohydride Di

Decent Essays
Show More
This experiment encompasses the reduction of 2-methylcyclohexanon to 2-methylcyclohexanol. The borohydride reduction experiment aim to use sodium borohydride with methanol to reduce ketone into secondary alcohol. This reaction take advantage of the hydride ion in order to initiate a nucleophilic addition to the carbonyl group of the ketone. The common reactant that are used in reduction experiment in the lab are sodium borohydride and lithium aluminum. Those two reactants contain hydride anion that facilitate the nucleophilic addition. The vigorous reaction of lithium aluminum with water, makes the sodium borohydride ideal for this experiment. During this reaction, the Cis and Trans isomer of the product can be yield. This is credit to the

Related Documents

  • Improved Essays

    Ethyl Ester Synthesis Lab Report
    • 988 Words
    • 4 Pages

    Ethyl Ester Synthesis Lab Report

    In a typical example, 1 g c-PEO-OH was dissolved in 30 mL anhydrous N-Methyl-2-pyrrolidone (NMP) solvent under dry argon atmosphere, to which 10 mL 2-bromoisobutyryl bromide was added at 0 °C dropwise for 30 min under vigorous stirring. The reaction mixture was then allowed to proceed at room temperature for 1 d. After that, the solution was concentrated by reduced pressure distillation to remove NMP solvent and excess 2-bromoisobutyryl bromide. The crude product was then washed with saturated aqueous solution of NaHCO3 and water sequentially for 3 times, dried over MgSO4, and precipitated in cold n-hexane to obtain a final brown viscous product. Preparation of c-PEO-N3 by substituting the Br on c-PEO-Br with azide functionalities…

    • 988 Words
    • 4 Pages
    Improved Essays
    Read More
  • Improved Essays

    Cyclohexanone Reaction Lab Report
    • 155 Words
    • 1 Pages

    Cyclohexanone Reaction Lab Report

    A possible chemical reason that this experiment yielded less than 100% cyclohexanone was due to the spontaneous decomposition of sodium hypochlorite, 2NaOCl = 2NaCl + O2, which decreased the amount of reactant present in the initial reaction when hypochlorous acid was formed, which was the oxidizing agent required to oxidize cyclohexanol into cyclohexanone. Sodium hypochlorite decomposed into O2 and NaCl due to a multitude of factors such as exposure to high temperatures, prolonged storage time or sunlight exposure. If a large enough quantity of the sodium hypochlorite was decomposed to limit the reaction that produced hypochlorous acid, the quantity of cyclohexanone produced may be affected. This would have resulted in a decrease in the production…

    • 155 Words
    • 1 Pages
    Improved Essays
    Read More
  • Improved Essays

    9-Fluorenone Lab Report
    • 1277 Words
    • 6 Pages

    9-Fluorenone Lab Report

    The reduction of this ketone produces secondary alcohols. Sodium borohydride is often used in this process because it reacts more rapidly with the carbonyl group than with the solvent. In this experiment, the reduction of 9-fluorenone using sodium borohydride to give 9-fluorenol will be examined. This reaction involves the transfer of a hydride ion from borohydride ion to the electrophilic carbonyl carbon with the accompanying transfer of the electron deficient boron atom to the carbonyl oxygen.1 The reaction is shown below: 10 is 9-fluorenone, 11 is the intermediate borate salt, and 12 is 9-fluorenol.…

    • 1277 Words
    • 6 Pages
    Improved Essays
    Read More
  • Improved Essays

    Addition Of 1-Hexene Lab Report
    • 535 Words
    • 3 Pages

    Addition Of 1-Hexene Lab Report

    The goal of this experiment is to synthesize a bromohexane compound from the addition of 1-hexene and HBr(aq) under reflux conditions. The product is then isolated and the regiochemistry is analyzed using chemical tests and known standards (1 Br, 2 Br) in order to determine if Markovnikov’s rule is followed. In general, Alkenes are able to undergo addition reactions due to the strength of their C-C -bond (60-65 kcal/mol) which is lower than the strength of a typical -bond (80-100 kcal/mol) between Carbon and other atoms. Adding a reagent across the double bond results in an exothermic reaction because one -bond is replaced by two higher energy -bonds. Accordingly, the addition of HBr(aq) to 1-Hexene involves the protonation of 1-hexene and is expected to produce a secondary carbocation, 2-bromohexane.…

    • 535 Words
    • 3 Pages
    Improved Essays
    Read More
  • Improved Essays

    4-Dihydropyridine Synthesis Lab Report
    • 734 Words
    • 3 Pages

    4-Dihydropyridine Synthesis Lab Report

    Experiment 15B was conducted in order to learn about the Hantzsch 1,4-Dihydropyridine synthesis mechanism. Furthermore, this lab will give students a better understanding of the terms pharmacophore and a privileged structure. In order for this reaction to occur an aldehyde, ammonia, and two equivalents of a B-ketoester go through a one-pot cyclocondensation reaction. After 1,4-dihydropyridine is formed, it is then oxidized to form its pyridine derivative. Alcohol or Acetic acid is then used as a refluxing solvent for this compound.…

    • 734 Words
    • 3 Pages
    Improved Essays
    Read More
  • Improved Essays

    Oleyl 9-Hydroxyoctadecanote Lab Report
    • 260 Words
    • 2 Pages

    Oleyl 9-Hydroxyoctadecanote Lab Report

    Synthesis of oleyl 9,(12)-hydroxy-10,(13)-oleioxyoctadecanoate (OLHYOODT) (4) The reaction mixture was heated on a magnetic heater and stirrer until it reached the experiment temperature; catalyst sulfuric acid (SA) and desiccant of silica gel (SG) were added to the mixture at that moment to remove the water during the reaction. The reaction temperatures were held constant within a range of ±1°C. A mixture of HYOODA 3 (5 g; 0.01 mol), oleyl alcohol (OL) (10 g; 0.02 mol) in a 250-mL three-neck flask equipped with a cooler, dropping funnel and thermometer was heated for 1 h at 90 °C. During the 1 h reaction SG was put in the oven at 180 °C for drying.…

    • 260 Words
    • 2 Pages
    Improved Essays
    Read More
  • Decent Essays

    Bromination Of Vanillin
    • 242 Words
    • 1 Pages

    Bromination Of Vanillin

    In this experiment, I have predicted the product of bromination of vanillin. The knowledge of electron-donating and electron-withdrawing substituents on the benzene ring and the position where they directed the bromine, helped me to accurately predict the major product of the reaction, which is 5-bromovanillin. In this experiment, I have reinforced stirring, vacuum filtration, and recrystallization skills. Also, I have learned how to use Melt-Temp apparatus to take a melting point of the final product. 5-bromovanillin was obtained in 98.3% yield from this reaction.…

    • 242 Words
    • 1 Pages
    Decent Essays
    Read More
  • Decent Essays

    Alkene To Alkyne
    • 515 Words
    • 3 Pages

    Alkene To Alkyne

    This mechanism produced meso-1,2-dibromo-1,2-diphenylethane as the sole products. Although, cis-1,2-dibromo-1,2-diphenylethane can be generated the substituent groups are too sterically hindered and the molecule too unstable to be a viable product in this reaction (Figure 2). This is evident in the notably different melting points of the isomers, cis-1,2-dibromo-1,2-diphenylethane has a melting point of 113°C while the melting point of meso-1,2-dibromo-1,2-diphenylethane is about 238°C (University of Windsor, 2015). Figure 1: Pyridinium tribromide generated in situ Figure 2: Isomers of 1,2-dibromo-1,2-diphenylethane vicinal dibromide Figure 3: Bromination Reaction Mechanism trans-stilbene 
 vicinal dibromide…

    • 515 Words
    • 3 Pages
    Decent Essays
    Read More
  • Improved Essays

    Hydroboration: Oxidation Of An Alkene
    • 630 Words
    • 3 Pages

    Hydroboration: Oxidation Of An Alkene

    Hydroboration/Oxidation of an Alkene Introduction: An alcohol can be added across the double bond of an alkene via hydration, which is the addition of a proton and alcohol group to the double bond. This reaction can yield either a Markovnikov alcohol or an Anti-Markovnikov alcohol. If the reaction is carried out in acidic conditions, the reaction yields a Markovnikov alcohol. The mechanism includes the formation of a carbocation intermediate, which has a lower activation energy when it is formed on the more substituted or resonance stabilized carbon. The nucleophile then attaches to the positive charge created by the carbocation, yielding the Markovnikov product.…

    • 630 Words
    • 3 Pages
    Improved Essays
    Read More
  • Great Essays

    Principle Of Green Chemistry
    • 1816 Words
    • 8 Pages

    Principle Of Green Chemistry

    Therefore, it is crucial to understand the effects of utilizing green chemistry principles and how the efficiency of a reaction can be assessed. Hence, the efficiency of the bromination and debromination reactions performed will be presented based on the analyses conducted on the collected products including melting range, TLC, IR, GC-MS and NMR; these procedures are used to assess the purity and identity of the products obtained from each reaction. Furthermore, green chemistry calculations including those for percent yield, atom economy, and E product will be presented which determines the efficiency of the bromination and debromination…

    • 1816 Words
    • 8 Pages
    Great Essays
    Read More
  • Improved Essays

    Paracetamol Lab Report
    • 651 Words
    • 3 Pages

    Paracetamol Lab Report

    These two steps were already carried out and 4 amino-phenol was the amine used in the first part of this experiment. 4 amino phenol and acetic anhydride undergo a nucleophilic addition-elimination reaction. A reaction mechanism is a step-by-step process when reactant molecules change in their geometry in order to produce new products. This occurs due to omission or addition of reagents, where bonds are broken down to form new ones4. 4 amino-phenol contains two functional groups, an OH and a NH2 group attached to a benzene ring while acetic anhydride is a derivative of a carboxylic acid group.…

    • 651 Words
    • 3 Pages
    Improved Essays
    Read More
  • Improved Essays

    Carbon Dioxide Research Paper
    • 711 Words
    • 3 Pages

    Carbon Dioxide Research Paper

    In this reaction it is the reaction between lithium hydroxide and water vapour to form lithium hydroxide monohydrate. LiOH(s) + H2O(g) LiOH•H2¬O(s) This reaction is followed by the endothermic formation of lithium carbonate. An endothermic reaction is the exact opposite of an exothermic reaction in which in an endothermic reaction, is a reaction that absorb energy from its surroundings in the form of heat.…

    • 711 Words
    • 3 Pages
    Improved Essays
    Read More
  • Superior Essays

    Recrystallization Of Acetanilide From Aniline
    • 1285 Words
    • 6 Pages

    Recrystallization Of Acetanilide From Aniline

    For this lab, a nucleophilic acyl substitution reaction was carried out to synthesize acetanilide from aniline and acetic anhydride. In this reaction, the lone pair of electrons…

    • 1285 Words
    • 6 Pages
    Superior Essays
    Read More
  • Superior Essays

    Acetone Dimethyl Ketone 2-Propane
    • 958 Words
    • 4 Pages

    Acetone Dimethyl Ketone 2-Propane

    Introduction Acetone (dimethyl ketone, 2-propane, CH3COCH3), formulation weight 58,079, isthe simplest and the most important of the ketones. It is a colourless, mobile, flammableliquid with a mildly pungent and somewhat aromatic odour. It is miscible in all proportionswith water and with organic solvents such as ether, methanol, ethyl alcohol, and esters. Acetone is used as a solvent for cellulose acetate and nitrocellulose, as a carrier for acetyleneand as a raw material for the chemical synthesis of a wide range of products such as ketene,methyl methacrylate, bisphenol A, diacetone alcohol mesityl oxide, methyl isobutyl ketone,hexylene glycol ( 2-methyl-2, 4-pentanediol ), and isophorone. Acetone is often produced as a by-product in the production…

    • 958 Words
    • 4 Pages
    Superior Essays
    Read More
  • Improved Essays

    2-Methoxyphenol Synthesis
    • 507 Words
    • 3 Pages

    2-Methoxyphenol Synthesis

    These highly reactive MOBs and MPBs intermediates undergoes numerous transformations such as cycloaddition reactions (ii) nucleophilic, electrophilic, and radical addition reactions, and (iii) photochemical reactions17. On account of their unique reactive features, rapid and easy generation they grabbed the attention of synthetic organic chemists. Synthesis of biaryl18,19 have received much attention in recent years because of their frequent occurrence in many natural products,20-22 pharmaceutically active compounds23-26 (Figure 18) and their wide applications in asymmetric synthesis,27-31 molecular catalysis 32-34 and material science35,36. In the past decades metal mediated…

    • 507 Words
    • 3 Pages
    Improved Essays
    Read More

Related Topics

Ready To Get Started?
Discover
Company
Follow
©2024 Cram.com
Privacy Policy |  About Ads |  Site Map |  Advertise  | 
  • Cookie Settings