a. Compare levels of eicosanoids, endotoxins (eg, LPS), and exotoxins within the ‘contaminated’ tissues and replicate study with fresh PBS. Comparing inflammatory cytokine levels may also be beneficial; however, given that they are implicated in / linked to a number of processes and pathologies one needs to know which one in particular to look at. b. If I understand what is being asked here, generally speaking bacteria enters the body leading to the communication of visceral inflammatory…
5. How does Leishmania tropica evade the immune system? Leishmania tropica surface molecule glycoprotein 63 (gp36) is found throughout the parasite surface and has the potential to degrade immunoglobulins, complement factors, and lysosomal proteins (Olivier et al. 2005). Gp36 can cleave C3b into an inactivated form and C3bi will appear on the surface of the membrane and hinders the formation of C5 convertase (Gupta et al. 2013). It is also able to use C3bi to bind to complement receptor 3…
Phage therapy could prove as an effective alternative to antibiotics. Phage is similar to antibiotics in the sense that it can destroy a bacterial infection but differs in the fact that the bacteria cannot develop resistance. As bacteria attempt to develop resistance to phage the phage counters by also evolving and mutating [5]. Another benefit of phage therapy is that once a phage has been applied to a bacterial infection it won’t stop until every single bacterium in the colony have been…
Are antibiotics overprescribed? Many people around the world are victims of bacterial antibiotic resistance. This is a result of doctors overprescribing antibiotics when unnecessary. Many antibiotics are prescribed for illnesses that caused by viruses. Doctors grab their prescription pad, when symptoms of common infection are shown in their patients, as there is no accurate diagnostic testing for bacterial infections. Bacteria become resistant to antibiotics through overexposure. On the other…
Current contact lens case hygiene guidelines of FDA involving with rubbing and cleaning with disinfecting solution and allow them to air dry with face down position.(http://www.fda.gov/downloads/ForConsumers/ConsumerUpdates/ucm048900.pdf. Accessed 2014/09/10 2008) But now there are very guidelines on air-drying location and position of the contact lens storage cases.(Y. T. Wu, Zhu, Willcox, et al. 2010a) Among optometrists there are still lots of discrepancies regarding recommendation about the…
Introduction Antibiotic resistance is a major threat to the health and wellbeing of the population. Antibiotic resistance has posed challenges to the public health community, while negatively impacting the general population (Another sentence of two about antibiotic resistance in general, the increasing trends and some figures). Today, carbapenemase producing-carbapenem resistant Enterobacteriaceae (CP-CRE) is a group of gram-negative bacteria that are challenging public health professionals…
Biological parameters were evaluated for the early diagnosis of neonatal sepsis . The most useful are enumeration of white blood cells (WBC ), total number of neutrophils (TN), the immature relative to the total neutrophils (I / T) and C-reactive protein (CRP) . [ 4-7] However, despite the number of available tests, none of them is absolutely reliable for early and accurate diagnosis . Several cytokines, such as IL -1B , IL-6 , IL- 8 and TNF -a are important mediators in the systemic host…
There are several strains of E. coli that exist, many of which are non-pathogenic in nature. E. coli forms a beneficial relationship in the intestinal tract, and takes on many helpful functions within the body. The functions include breaking down nutrients, developing signals to regulate the immune system, and even protection against other pathogens. The broad categories of E. coli are separated into diarrheagenic E. coli and extraintestinal pathogenic E. coli, which includes uropathogenic E.…
Strategies Raising awareness (3) among the public and healthcare professionals through campaigns and events can help to educate people to the risks of antibiotic resistance and measures they can take to reduce the risk of it. Since 2008 there has been an European Antibiotic awareness day each year which has been found to be not only successful in raising awareness and changing the behaviour of healthcare professionals and the public in the way that they handle antibiotics but it was also quite…
The civil rights movement was at its height during the 60’s. After Dr. Martin Luther King Jr.’s assassination, the people’s reaction was to turn to violence. Cesar Chavez pleads with the people to help them see that the most powerful and successful way to bring change is to use nonviolence. His use of striking diction, juxtapositions, and appeals to the fundamental beliefs of his readers leaves his audience with little doubt as to the proper course of action. Chavez, less than 10 words into his…