Some types of tests include: skin sensitization, acute oral toxicity, repeat dose and subchronic toxicity. Most of these tests mentioned are performed on rabbits, guinea pigs, mice, and rats. Each test is performed over a certain amount of time. For example, the repeat dose is a 28 day process and the subchronic toxicity is a 90 day process. The repeat dose consists of 40 rats for a 28 day process, the rats will either be force fed, have the chemical rubbed on skin, or will breathe in the chemical daily for the amount of time. This type of test looks for cell and organ deficiency. Once the time is up, the animal is killed and its body is examined. The examination is what determines whether the chemical is safe to use or
Some types of tests include: skin sensitization, acute oral toxicity, repeat dose and subchronic toxicity. Most of these tests mentioned are performed on rabbits, guinea pigs, mice, and rats. Each test is performed over a certain amount of time. For example, the repeat dose is a 28 day process and the subchronic toxicity is a 90 day process. The repeat dose consists of 40 rats for a 28 day process, the rats will either be force fed, have the chemical rubbed on skin, or will breathe in the chemical daily for the amount of time. This type of test looks for cell and organ deficiency. Once the time is up, the animal is killed and its body is examined. The examination is what determines whether the chemical is safe to use or